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WWC1 Antikörper (AA 351-450) (Biotin)

WWC1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1392055
  • Target Alle WWC1 Antikörper anzeigen
    WWC1 (WW and C2 Domain Containing 1 (WWC1))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reaktivität
    • 36
    • 19
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 34
    • 3
    Kaninchen
    Klonalität
    • 34
    • 3
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WWC1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 37
    • 16
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KIBRA
    Isotyp
    IgG
    Top Product
    Discover our top product WWC1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    WWC1 (WW and C2 Domain Containing 1 (WWC1))
    Andere Bezeichnung
    KIBRA (WWC1 Produkte)
    Synonyme
    CG12600 antikoerper, CG33967 antikoerper, CG7552 antikoerper, Dmel\\CG33967 antikoerper, Kibra antikoerper, ORE-2 antikoerper, RE26350 antikoerper, kib antikoerper, l(3)02404 antikoerper, l(3)j5C3 antikoerper, l(3)neo42 antikoerper, HBEBP3 antikoerper, HBEBP36 antikoerper, KIBRA antikoerper, AA408228 antikoerper, AU017197 antikoerper, BC037006 antikoerper, mKIAA0869 antikoerper, CG33967 gene product from transcript CG33967-RB antikoerper, WW and C2 domain containing 1 antikoerper, WW, C2 and coiled-coil domain containing 1 antikoerper, kibra antikoerper, WWC1 antikoerper, Wwc1 antikoerper
    Hintergrund

    Synonyms: KIBRA, HBEBP3, HBEBP36, MEMRYQTL, PPP1R168, Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, WW domain-containing protein 1, WWC1, KIAA0869

    Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.

    Gen-ID
    23286
    UniProt
    Q8IX03
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