RPSA/Laminin Receptor Antikörper (AA 190-240)
Kurzübersicht für RPSA/Laminin Receptor Antikörper (AA 190-240) (ABIN5690234)
Target
Alle RPSA/Laminin Receptor (RPSA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 190-240
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Spezifität
 - RPSA antibody is human, mouse and rat reactive.
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Aufreinigung
 - RPSA antibody is affinity chromatography purified via peptide column.
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Immunogen
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                        RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA.
The immunogen is located within amino acids 190 - 240 of RPSA. - 
                                            
Isotyp
 - IgG
 
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Applikationshinweise
 - RPSA antibody can be used for detection of RPSA by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 mg/mL
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Buffer
 - RPSA antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C,-20 °C
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Informationen zur Lagerung
 - RPSA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
 
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- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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Andere Bezeichnung
 - RPSA
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Hintergrund
 - The 40S ribosomal protein SA (RPSA) is a high-affinity, non-integrin family, laminin receptor, also known as 67 kDa laminin receptor or 37 kDa laminin receptor precursor (37LRP) (1). Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes and have been implicated in a variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis (2). RPSA is overexpressed in multiple types of cancers and has recently been shown to act as a cancer-specific death receptor (3).
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Molekulargewicht
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                        Predicted: 32 kDa 
Observed: 32 kDa - 
                                            
Gen-ID
 - 3921
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NCBI Accession
 - NP_002286
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UniProt
 - P08865
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Pathways
 - Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
 
Target
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