RHOT1 Antikörper (AA 40-90)

Produktnummer ABIN5690226

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RHOT1 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für RHOT1 Antikörper (AA 40-90) (ABIN5690226)

Target: RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RHOT1 Antikörper

Bindungsspezifität: AA 40-90

Spezifität: RHOT1 antibody is human, mouse and rat reactive. At least three isoforms of RHOT1 are known to exist, this antibody will detect all three isoforms.

Aufreinigung: RHOT1 antibody is affinity chromatography purified via peptide column.

Immunogen: RHOT1 antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOT1.

The immunogen is located within amino acids 40 - 90 of RHOT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RHOT1 antibody can be used for detection of RHOT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RHOT1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: RHOT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu RHOT1

Target: RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))

Andere Bezeichnung: RHOT1

Hintergrund: The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria (1). RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria (2,3). Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility (4).

Molekulargewicht: Predicted: 76 kDa

Observed: 78 kDa

Gen-ID: 55288

NCBI Accession: NP_001028740

UniProt: Q8IXI2