GOLGA5 Antikörper (AA 540-590)

Produktnummer ABIN5689977

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GOLGA5 in WB, ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für GOLGA5 Antikörper (AA 540-590) (ABIN5689977)

Target: GOLGA5 (Golgin A5 (GOLGA5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOLGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GOLGA5 Antikörper

Bindungsspezifität: AA 540-590

Spezifität: GOLGA5 antibody is human, mouse and rat reactive. Two isoforms of GOLGA5 exist due to alternative splicing events.

Aufreinigung: GOLGA5 Antibody is affinity chromatography purified via peptide column.

Immunogen: GOLGA5 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GOLGA5.

The immunogen is located within amino acids 540 - 590 of GOLGA5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GOLGA5 antibody can be used for detection of GOLGA5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GOLGA5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: GOLGA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GOLGA5

Target: GOLGA5 (Golgin A5 (GOLGA5))

Andere Bezeichnung: GOLGA5

Hintergrund: GOLGA5 Antibody: GOLGA5 (Golgi autoantigen, subfamily A, member 5), also known as GOLGA84, RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein that is involved in maintaining Golgi structure (1). It is localized to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack (1,2). As a mitotic phosphoprotein, GOLGA5 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport (3,4). Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) (5).

Molekulargewicht: Predicted: 64, 80 kDa

Observed: 65, 78 kDa

Gen-ID: 9950

NCBI Accession: NP_005104

UniProt: Q8TBA6