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ATM Interactor Antikörper (AA 200-250)

ATMIN Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5689887
  • Target Alle ATM Interactor (ATMIN) Antikörper anzeigen
    ATM Interactor (ATMIN)
    Bindungsspezifität
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 200-250
    Reaktivität
    • 21
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 19
    • 2
    Kaninchen
    Klonalität
    • 21
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATM Interactor Antikörper ist unkonjugiert
    Applikation
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist.
    Aufreinigung
    ATMIN antibody is affinity chromatography purified via peptide column.
    Immunogen
    ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN.

    The immunogen is located within amino acids 200 - 250 of ATMIN.
    Isotyp
    IgG
    Top Product
    Discover our top product ATMIN Primärantikörper
  • Applikationshinweise
    ATMIN antibody can be used for detection of ATMIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 2.5 μ,g/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    ATMIN Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    ATMIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    ATM Interactor (ATMIN)
    Andere Bezeichnung
    ATMIN (ATMIN Produkte)
    Synonyme
    Asciz antikoerper, mKIAA0431 antikoerper, RGD1305781 antikoerper, ASCIZ antikoerper, ZNF822 antikoerper, ATM interactor antikoerper, ATM interactor L homeolog antikoerper, Atmin antikoerper, ATMIN antikoerper, atmin.L antikoerper, atmin antikoerper
    Hintergrund
    The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).
    Molekulargewicht
    Predicted: 73, 79, 91 kDa

    Observed: 72 kDa
    Gen-ID
    23300
    NCBI Accession
    NP_056066
    UniProt
    O43313
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