APOE Antikörper (AA 220-270)

Produktnummer ABIN5689876

Der Kaninchen Polyklonal anti-APOE Antikörper wird verwendet zum Nachweis von APOE in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für APOE Antikörper (AA 220-270) (ABIN5689876)

Target: APOE (Apolipoprotein E (APOE))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-APOE Antikörper

Bindungsspezifität: AA 220-270

Aufreinigung: APO-E Antibody is affinity chromatography purified via peptide column.

Immunogen: APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E.

The immunogen is located within amino acids 220 - 270 of APO-E.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: APO-E antibody can be used for detection of APO-E by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: APO-E Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: APO-E antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu APOE

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: APO-E

Hintergrund: APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Molekulargewicht: Predicted: 35 kDa

Observed: 34 kDa

Gen-ID: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism