APOE Antikörper (AA 220-270)

Produktnummer ABIN5689876

Der Kaninchen Polyklonal Anti-APOE-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, APOE in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für APOE Antikörper (AA 220-270) (ABIN5689876)

Target: APOE (Apolipoprotein E (APOE))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-APOE Antikörper

Bindungsspezifität: AA 220-270

Aufreinigung: APO-E Antibody is affinity chromatography purified via peptide column.

Immunogen: APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E.

The immunogen is located within amino acids 220 - 270 of APO-E.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: APO-E antibody can be used for detection of APO-E by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: APO-E Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: APO-E antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu APOE

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: APO-E

Hintergrund: APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Molekulargewicht: Predicted: 35 kDa

Observed: 34 kDa

Gen-ID: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism