AIMP1 Antikörper (AA 240-290)

Produktnummer ABIN5688956

Der Kaninchen Polyklonal anti-AIMP1 Antikörper (ABIN5688956) detektiert spezifisch AIMP1 in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für AIMP1 Antikörper (AA 240-290) (ABIN5688956)

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AIMP1 Antikörper

Bindungsspezifität: AA 240-290

Spezifität: AIMP1 antibody is human, mouse and rat reactive. At least two isoforms of AIMP1 are known to exist, this antibody will recognize both isoforms. AIMP1 antibody is predicted to not cross-react with AIMP2.

Aufreinigung: AIMP1 antibody is affinity chromatography purified via peptide column.

Immunogen: AIMP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AIMP1.

The immunogen is located within amino acids 240 - 290 of AIMP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AIMP1 antibody can be used for detection of AIMP1 by Western blot at 1 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AIMP1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: AIMP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu AIMP1

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Andere Bezeichnung: AIMP1

Hintergrund: AIMP1 (Endothelial monocyte-activating polypeptide II, EMAP2) is a proinflammatory cytokine for monocytes and granulocytes (1). It is specifically induced by apoptosis and is involved in the control of angiogenesis, inflammation, and wound healing (1,2). AIMP1 was identified as one of three auxiliary factors of the mammalian aminoacyl tRNA synthetase (ARS) complex. It binds and facilitates the catalytic reaction of arginyl-tRNA synthetase (2,3). Recent studies show that CD23 plays an essential role in the AIMP1-induced immune response and might be a target in the treatment of inflammatory diseases (4).

Molekulargewicht: Predicted: 46 kDa

Observed: 36 kDa

Gen-ID: 9255

NCBI Accession: NP_001135888

UniProt: Q12904