Synaptotagmin Antikörper (Ser309)

Produktnummer ABIN5688918

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Synaptotagmin in WB und IHC. Er zeigt eine Reaktivität gegenüber Ratte, Maus und Human.

Kurzübersicht für Synaptotagmin Antikörper (Ser309) (ABIN5688918)

Target: Synaptotagmin (SYT)

Reaktivität: Ratte, Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synaptotagmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Synaptotagmin Antikörper

Bindungsspezifität: Ser309

Spezifität: Synaptotagmin antibody is specific for Mr 60 - 62k synaptotagmin phosphorylated at Ser309.

Aufreinigung: Affinity Purified

Immunogen: Synaptotagmin (Ser309) polyclonal antibody was raised against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Ser309 of synaptotagmin.

Anwendungsinformationen

Applikationshinweise: Applications include Dot Blots (DB) and Western Blots (WB). Suitability for Immunohistochemistry (IHC) has not yet been determined. Human, mouse, and rat have 100 % amino acid sequence identity with the antigen used to raise the antibody. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.

Details zu Synaptotagmin

Target: Synaptotagmin (SYT)

Andere Bezeichnung: Synaptotagmin

Hintergrund: Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis. Moreover recent studies indicate that the protein also plays a key role in endocytosis. Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission.

Molekulargewicht: 60/62 kDa

Gen-ID: 25716

UniProt: P21707