Glycogen Synthase Antikörper (pSer9)

Produktnummer ABIN5688910

Produktdetails anti-Glycogen Synthase Antikörper

Target: Glycogen Synthase (GYS)

Bindungsspezifität: pSer9

Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Xenopus laevis, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glycogen Synthase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity Purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser9 of GSK3b.

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with human, mouse, chicken, bovine, canine, non-human primate, Zebra fish and Xenopus based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Glycogen synthase antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu Glycogen Synthase

Target: Glycogen Synthase (GYS)

Andere Bezeichnung: Glycogen synthase (GYS Produkte)

Hintergrund: Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that is involved in the regulation of many signaling pathways. To date, 2 isoforms have been identified: GSK3alpha and GSK3beta. Specifically, GSK3beta has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways (Papkoff and Aikawa 1998). It has been suggested that Ser9 phosphorylation underlies the inhibition of GSK3beta by insulin (Sutherland et al., 1993).

Molekulargewicht: 46 kDa

Gen-ID: 84027

UniProt: P18266