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Glycogen Synthase Antikörper (pSer9)

Der Kaninchen Polyklonal Anti-Glycogen Synthase-Antikörper wurde für WB validiert. Er ist geeignet, Glycogen Synthase in Proben von Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Xenopus laevis und Zebrafisch (Danio rerio) zu detektieren.
Produktnummer ABIN5688910

Kurzübersicht für Glycogen Synthase Antikörper (pSer9) (ABIN5688910)

Target

Alle Glycogen Synthase (GYS) Antikörper anzeigen
Glycogen Synthase (GYS)

Reaktivität

Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Xenopus laevis, Zebrafisch (Danio rerio)

Wirt

  • 20
Kaninchen

Klonalität

  • 11
  • 9
Polyklonal

Konjugat

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glycogen Synthase Antikörper ist unkonjugiert

Applikation

  • 13
  • 9
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer9

    Aufreinigung

    Affinity Purified

    Immunogen

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser9 of GSK3b.
  • Applikationshinweise

    The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with human, mouse, chicken, bovine, canine, non-human primate, Zebra fish and Xenopus based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Glycogen synthase antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • Target

    Glycogen Synthase (GYS)

    Andere Bezeichnung

    Glycogen synthase

    Hintergrund

    Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that is involved in the regulation of many signaling pathways. To date, 2 isoforms have been identified: GSK3alpha and GSK3beta. Specifically, GSK3beta has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways (Papkoff and Aikawa 1998). It has been suggested that Ser9 phosphorylation underlies the inhibition of GSK3beta by insulin (Sutherland et al., 1993).

    Molekulargewicht

    46 kDa

    Gen-ID

    84027

    UniProt

    P18266
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