STXBP1 Antikörper (pSer515)

Produktnummer ABIN5688903

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STXBP1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Huhn und Xenopus laevis.

Kurzübersicht für STXBP1 Antikörper (pSer515) (ABIN5688903)

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STXBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-STXBP1 Antikörper

Bindungsspezifität: pSer515

Aufreinigung: Affinity Purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser515 of Munc-18.

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, chicken, human, mouse, non-human primates and Xenopus based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Munc-18 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu STXBP1

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Andere Bezeichnung: Munc-18

Hintergrund: Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein (Sassa et al., 1996).

Molekulargewicht: 65 kDa

Gen-ID: 81804

UniProt: Q62753

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport