MAP2K5 Antikörper (pSer311, pThr315)

Produktnummer ABIN5688896

Der Kaninchen Polyklonal anti-MAP2K5 Antikörper (ABIN5688896) detektiert spezifisch MAP2K5 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Hund, Rind (Kuh), Huhn, Xenopus laevis und Zebrafisch (Danio rerio).

Kurzübersicht für MAP2K5 Antikörper (pSer311, pThr315) (ABIN5688896)

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Huhn, Xenopus laevis, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP2K5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP2K5 Antikörper

Bindungsspezifität: pSer311, pThr315

Aufreinigung: Affinity Purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser311, Thr315 of MEK5.

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with mouse, human, chicken, bovine, canine, non-human primate, Xenopus, and Zebrafish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: MEK5 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Andere Bezeichnung: MEK5

Hintergrund: MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 (Zhou et al., 1995) whereas MEK5 itself is regulated by MEKK3 (Chao et al., 1999). An important link between MEK5 and metastatic prostrate cancer has been demonstrated (Mehta et.al., 2003). Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation (Cameron et al., 2004).

Molekulargewicht: 49 kDa

Gen-ID: 29568

UniProt: Q62862

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung