14-3-3 theta Antikörper (C-Term)

Produktnummer ABIN5688864

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch 14-3-3 theta in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Huhn, Hund, Xenopus laevis und Zebrafisch (Danio rerio).

Kurzübersicht für 14-3-3 theta Antikörper (C-Term) (ABIN5688864)

Target: 14-3-3 theta (YWHAQ)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Huhn, Hund, Xenopus laevis, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 14-3-3 theta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-14-3-3 theta Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity Purified

Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of 14-3-3 protein, conjugated to keyhole limpet hemocyanin (KLH).

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, chicken, human, mouse, non-human primates, Xenopus and zebra fish based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: 14-3-3 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu 14-3-3 theta

Target: 14-3-3 theta (YWHAQ)

Andere Bezeichnung: 14-3-3

Hintergrund: 14-3-3 proteins are a family of highly conserved proteins that appear to have multiple roles in cell signaling (Bridges and Moorhead, 2005). The proteins are abundantly expressed in the brain and have been detected in the cerebrospinal fluid of patients with different neurological disorders (Berg et al., 2003). 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms (Silhan et al., 2004, Dougherty and Morrison, 2004). The 14-3-3 proteins affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking.

Molekulargewicht: 29 kDa

Gen-ID: 56011

UniProt: P35213

Pathways: Apoptose, Myometrial Relaxation and Contraction