TUBB3 Antikörper

Produktnummer ABIN5688672

Dieser Maus Monoklonal Antikörper detektiert spezifisch TUBB3 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Säugetier.

Kurzübersicht für TUBB3 Antikörper (ABIN5688672)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reaktivität: Säugetier

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: AA10

Produktdetails anti-TUBB3 Antikörper

Spezifität: Specific for the ~55  kDa beta III tubulin protein. This clone is similar to the monoclonal antibody Tuj1.

Aufreinigung: Protein G purified

Immunogen: Synthetic peptide corresponding to beta III tubulin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Beta III Tubulin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Andere Bezeichnung: Beta III Tubulin

Hintergrund: Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)

Molekulargewicht: 55 kDa

Gen-ID: 246118

UniProt: Q4QRB4

Pathways: Microtubule Dynamics, M Phase