LAG3 Antikörper (N-Term) (Atto 590)
Kurzübersicht für LAG3 Antikörper (N-Term) (Atto 590) (ABIN5688372)
Target
Alle LAG3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- N-Term
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Spezifität
- Recognizes human LAG-3.
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Reinheit
- > 95% (SDS-PAGE)
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Immunogen
- Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Liquid. In PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Andere Bezeichnung
- LAG-3
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Hintergrund
- Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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Gen-ID
- 3902
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UniProt
- P18627
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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