POR Antikörper (Internal Region)

Produktnummer ABIN568710

Der Ziege Polyklonal anti-POR Antikörper (ABIN568710) detektiert spezifisch POR in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund und Schwein.

Kurzübersicht für POR Antikörper (Internal Region) (ABIN568710)

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser POR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-POR Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-TNPPRTNVLY E

Spezifität: Recognizes Cytochrome P450 Reductase (CYPOR).

Kreuzreaktivität (Details): Species reactivity (expected):Dog, Cow, Pig, Rabbit.
Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_000932.3. Genename: POR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu POR

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Andere Bezeichnung: Cytochrome P450 Reductase

Hintergrund: P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.Synonyms: CPR, CYPOR, NADPH--cytochrome P450 reductase, P450R, POR

Gen-ID: 5447

NCBI Accession: NP_000932

UniProt: P16435

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interaktom