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CIRBP Antikörper (C-Term)
CIRBP
Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)
WB, IHC (p), EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-CIRBP Antikörper
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Target
Alle CIRBP Antikörper anzeigen
CIRBP
(Cold Inducible RNA Binding Protein (CIRBP))
Bindungsspezifität
Alle Epitope für CIRBP Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für CIRBP Antikörper
Human, Maus, Ratte, Hund, Rind (Kuh)
Wirt
Alle Wirte für CIRBP Antikörper
Ziege
Klonalität
Alle Klonalitäten für CIRBP Antikörper
Polyklonal
Konjugat
Alle Konjugate für CIRBP Antikörper
Dieser CIRBP Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CIRBP Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequenz
C-RDSYDSYATH NE
Spezifität
Recognizes CIRBP (aa 161-172).
Kreuzreaktivität (Details)
Species reactivity (expected):Rat, Canine (Dog), Bovine. Species reactivity (tested):Human, Mouse.
Aufreinigung
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the C-Terminus of the protein sequence according to NP_001271.1. Genename: CIRBP
Top Product
Discover our top product CIRBP Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu CIRBP
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Target
CIRBP
(Cold Inducible RNA Binding Protein (CIRBP))
Andere Bezeichnung
CIRBP (CIRBP Produkte )
Synonyme
CIRP antikoerper, Cirp antikoerper, R74941 antikoerper, Xcirp antikoerper, cirbp antikoerper, cirbp-a antikoerper, cirbp2 antikoerper, cirp antikoerper, cirp1 antikoerper, cirp2 antikoerper, xcirp2 antikoerper, XCIRP antikoerper, XCIRP-1 antikoerper, cirbp-b antikoerper, cirp-1 antikoerper, APBP-1 antikoerper, zgc:136559 antikoerper, CIRBP antikoerper, A18 hnRNP antikoerper, cold inducible RNA binding protein antikoerper, cold-inducible RNA-binding protein antikoerper, cold inducible RNA binding protein S homeolog antikoerper, cold inducible RNA binding protein L homeolog antikoerper, cold inducible RNA binding protein b antikoerper, CIRBP antikoerper, EDI_107320 antikoerper, Cirbp antikoerper, cirbp.S antikoerper, cirbp.L antikoerper, cirbp antikoerper, cirbpb antikoerper
Hintergrund
CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. It acts as a translational repressor. CIRBP is an immortalized gene in murine primary cells. CIRBP promotes assembly of stress granules (SGs), when overexpressed. It is a potential proto-oncogenic proteins upon overexpression. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature.Synonyms: A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP
Gen-ID
1153
NCBI Accession
NP_001271
UniProt
Q14011
Pathways
Ribonucleoprotein Complex Subunit Organization
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