Histone Cluster 2, H4a (HIST2H4A) (3meLys20) Antikörper

Produktnummer ABIN5684094

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Histone Cluster 2, H4a (HIST2H4A) (3meLys20) Antikörper (ABIN5684094)

Target: Histone Cluster 2, H4a (HIST2H4A)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 7A2A7

Produktdetails

Bindungsspezifität: 3meLys20

Verwendungszweck: HIST2H4A (20Me3) Antibody

Aufreinigung: Purified antibody

Immunogen: Synthesized peptide of human HIST2H4A (AA: GGAKRHRK(Me3)VLRDNIQ) .

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Antigendetails

Target: Histone Cluster 2, H4a (HIST2H4A)

Andere Bezeichnung: HIST2H4A

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy.

Molekulargewicht: 11.4 kDa

UniProt: P62805

Pathways: Telomere Maintenance