Histone Cluster 2, H4a (HIST2H4A) (Middle Region) Antikörper

Produktnummer ABIN2788644

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Histone Cluster 2, H4a in WB. Es zeigt Reaktivität gegenüber Proben von Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für Histone Cluster 2, H4a (HIST2H4A) (Middle Region) Antikörper (ABIN2788644)

Target: Histone Cluster 2, H4a (HIST2H4A)

Reaktivität: Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: Middle Region

Verwendungszweck: Hist2h4 Antibody - middle region

Sequenz: LARRGGVKRI SGLIYEETRG VLKVFLENVI RDAVTYTEHA KRKTVTAMDV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Hist2h4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60985-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: Histone Cluster 2, H4a (HIST2H4A)

Andere Bezeichnung: Hist2h4

Hintergrund:

Background Information: Hist2h4 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Name: Histone cluster 2, H4

Alternative Symbols: H4, H4c1, H4c2, H4c3, H4c4, H4c6, H4c8, H4c9, H4c11, H4c12, H4f16, Hist2, X04652, Hist2h4

Protein Name: Histone H4

Molekulargewicht: 11kDa

Gen-ID: 97122

NCBI Accession: NP_291074

UniProt: P62806

Pathways: Telomere Maintenance