LILRB2 Antikörper (AA 51-184)
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- Target Alle LILRB2 Antikörper anzeigen
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
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Bindungsspezifität
- AA 51-184
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LILRB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- LILRB2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human LILRB2 (AA: 51-184) expressed in E. Coli.
- Klon
- 2G7E11
- Isotyp
- IgG2a
- Top Product
- Discover our top product LILRB2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
- Andere Bezeichnung
- LILRB2 (LILRB2 Produkte)
- Hintergrund
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Description: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: ILT4, LIR2, CD85D, ILT-4, LIR-2, MIR10, MIR-10
- Molekulargewicht
- 65kDa
- Gen-ID
- 10288
- HGNC
- 8771
- UniProt
- Q8N423
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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