TXNIP Antikörper

Produktnummer ABIN567794

Produktdetails anti-TXNIP Antikörper

Target: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TXNIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody reacts with Txnip/VDUP1 (50 kDa) on Western blotting and Immunoprecipitation.

Aufreinigung: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogen: Human recombinant VDUP-1/Txnip.

Klon: JY2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu TXNIP

Target: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Andere Bezeichnung: TXNIP / VDUP1 (TXNIP Produkte)

Synonyme: EST01027 antikoerper, HHCPA78 antikoerper, THIF antikoerper, VDUP1 antikoerper, Gm348 antikoerper, Trf3 antikoerper, TBP2 antikoerper, TRF3 antikoerper, 1200008J08Rik antikoerper, AA682105 antikoerper, Hyplip1 antikoerper, Tbp-2 antikoerper, Vdup1 antikoerper, sb:cb368 antikoerper, txnip antikoerper, thioredoxin interacting protein antikoerper, TATA box binding protein like 2 antikoerper, TATA-box binding protein like 2 antikoerper, thioredoxin interacting protein L homeolog antikoerper, thioredoxin interacting protein a antikoerper, TXNIP antikoerper, Tbpl2 antikoerper, TBPL2 antikoerper, Txnip antikoerper, txnip.L antikoerper, txnip antikoerper, txnipa antikoerper

Hintergrund: Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX. It has been reported that Txnip plays important roles in diverse cellular processes, including the regulation of cellular redox balance, apoptosis, proliferation, and differentiation.Synonyms: Thioredoxin-binding protein 2, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1

Gen-ID: 10628

NCBI Accession: NP_006463

UniProt: Q9H3M7

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome