TXNIP Antikörper
Kurzübersicht für TXNIP Antikörper (ABIN567793)
Target
Alle TXNIP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts with VDUP-1 (50 kDa) by Western blotting.
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Aufreinigung
- Protein-A Agarose Chromatography of hybridoma supernatant.
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Immunogen
- Human recombinant VDUP-1/Txnip.
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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Andere Bezeichnung
- TXNIP / VDUP1
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Hintergrund
- Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX.Synonyms: Thioredoxin-binding protein 2, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1
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Gen-ID
- 10628
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NCBI Accession
- NP_006463
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UniProt
- Q9H3M7
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Pathways
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
Target
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