RAD21 Antikörper (C-Term)
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- Target Alle RAD21 Antikörper anzeigen
- RAD21 (RAD21 Homolog (RAD21))
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Bindungsspezifität
- AA 544-631, C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser RAD21 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Spezifität
- This antibody reacts with Cohesin (120 kDa) on Western blotting.
- Aufreinigung
- Protein-A Agarose Chromatography of hybridoma supernatant.
- Immunogen
- Recombinant C-terminal fragment (544-631 aa) of Scc1 subunit of Human Cohesin (hRad21).
- Klon
- CM110-2C10
- Isotyp
- IgG1
- Top Product
- Discover our top product RAD21 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Target
- RAD21 (RAD21 Homolog (RAD21))
- Andere Bezeichnung
- RAD21 (RAD21 Produkte)
- Hintergrund
- Cohesin in eukaryotic cells is mediated by a multisubunit protein complex. Cohesin consists of four proteins: Smc1, Smc3, Scc1/Mcd1/hRad21, which is called kleisin and is the target of the protease separase, and Scc3/Irr1. Cohesin holds sister chromatids together until they separate into daughter cells during mitosis and also prevents splitting of chromosomes once bipolar attachments are made.Synonyms: Double-strand-break repair protein rad21 homolog, HR21, KIAA0078, NXP1, Nuclear matrix protein 1, SCC1 homolog
- Gen-ID
- 5885
- NCBI Accession
- NP_006256
- UniProt
- O60216
- Pathways
- Positive Regulation of Endopeptidase Activity
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