RAD21 Antikörper (C-Term)

Produktnummer ABIN567792

Dieses Anti-RAD21-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von RAD21 in WB und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für RAD21 Antikörper (C-Term) (ABIN567792)

Target: RAD21 (RAD21 Homolog (RAD21))

Reaktivität: Human, Maus, Ratte

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser RAD21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: CM110-2C10

Produktdetails anti-RAD21 Antikörper

Bindungsspezifität: AA 544-631, C-Term

Spezifität: This antibody reacts with Cohesin (120 kDa) on Western blotting.

Aufreinigung: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogen: Recombinant C-terminal fragment (544-631 aa) of Scc1 subunit of Human Cohesin (hRad21).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Andere Bezeichnung: RAD21

Hintergrund: Cohesin in eukaryotic cells is mediated by a multisubunit protein complex. Cohesin consists of four proteins: Smc1, Smc3, Scc1/Mcd1/hRad21, which is called kleisin and is the target of the protease separase, and Scc3/Irr1. Cohesin holds sister chromatids together until they separate into daughter cells during mitosis and also prevents splitting of chromosomes once bipolar attachments are made.Synonyms: Double-strand-break repair protein rad21 homolog, HR21, KIAA0078, NXP1, Nuclear matrix protein 1, SCC1 homolog

Gen-ID: 5885

NCBI Accession: NP_006256

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity