SMAD2 Antikörper (pSer250)
Kurzübersicht für SMAD2 Antikörper (pSer250) (ABIN5675082)
Target
Alle SMAD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer250
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Kreuzreaktivität
- Maus, Ratte
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Homologie
- Human,Dog,Cow,Pig
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Anti-phospho-Smad2 (Ser250)
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
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Andere Bezeichnung
- Smad2
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Hintergrund
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Synonyms: Mothers against decapentaplegic homolog 2, SMAD2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, MADH2, MADR2
Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.
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Gen-ID
- 4087
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UniProt
- Q15796
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Pathways
- Zellzyklus, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
Target
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