TMEM43 Antikörper (N-Term)

Produktnummer ABIN5673734

Dieser Anti-TMEM43 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von TMEM43 in WB. Geeignet für Human.

Kurzübersicht für TMEM43 Antikörper (N-Term) (ABIN5673734)

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TMEM43 Antikörper

Bindungsspezifität: N-Term

Sequenz: ANYSSTSTRR EHVKVKTSSQ PGFLERLSET SGGMFVGLMA FLLSFYLIFT

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TMEM43

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TMEM43

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Andere Bezeichnung: TMEM43

Hintergrund: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Alias Symbols: LUMA, ARVC5, ARVD5, EDMD7

Protein Size: 400

Gen-ID: 79188

NCBI Accession: NM_024334, NP_077310

UniProt: Q9BTV4