Bystin-Like Antikörper (C-Term)

Produktnummer ABIN5672937

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Bystin-Like in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Bystin-Like Antikörper (C-Term) (ABIN5672937)

Target: Bystin-Like (BYSL)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bystin-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Bystin-Like Antikörper

Bindungsspezifität: C-Term

Sequenz: LTLVQRYKAD LATDQKEALL ELLRLQPHPQ LSPEIRRELQ SAVPRDVEDV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BYSL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Bystin-Like

Target: Bystin-Like (BYSL)

Andere Bezeichnung: BYSL

Hintergrund: Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.

Alias Symbols: BYSTIN

Protein Size: 437

Gen-ID: 705

NCBI Accession: NM_004053, NP_004044

UniProt: Q13895

Pathways: Cellular Response to Molecule of Bacterial Origin