RASSF5 Antikörper (N-Term)

Produktnummer ABIN5672597

Der Kaninchen Polyklonal anti-RASSF5 Antikörper (ABIN5672597) detektiert spezifisch RASSF5 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RASSF5 Antikörper (N-Term) (ABIN5672597)

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASSF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RASSF5 Antikörper

Bindungsspezifität: N-Term

Sequenz: IGQRPYPLLL DPEPPRYLQS LSGPELPPPP PDRSSRLCVP APLSTAPGAR

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RASSF5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RASSF5

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Andere Bezeichnung: RASSF5

Hintergrund: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: RAPL, Maxp1, NORE1, NORE1A, NORE1B, RASSF3

Protein Size: 418

Gen-ID: 83593

NCBI Accession: NM_182663, NP_872604

UniProt: Q8WWW0

Pathways: T-Zell Rezeptor Signalweg