Keratin 6B Antikörper (C-Term)

Produktnummer ABIN5672206

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Keratin 6B in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Keratin 6B Antikörper (C-Term) (ABIN5672206)

Target: Keratin 6B (KRT6B)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Keratin 6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Keratin 6B Antikörper

Bindungsspezifität: C-Term

Sequenz: SSGYGGASGV GSGLGLGGGS SYSYGSGLGV GGGFSSSSGR ATGGGLSSVG

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KRT6B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Keratin 6B

Target: Keratin 6B (KRT6B)

Andere Bezeichnung: KRT6B

Hintergrund: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Alias Symbols: K6B, PC2, PC4, CK6B, CK-6B, KRTL1

Protein Size: 564

Gen-ID: 3854

NCBI Accession: NM_005555, NP_005546

UniProt: P04259