Rekombinanter CD55 Antikörper

Produktnummer ABIN5668199

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch CD55 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter CD55 Antikörper (ABIN5668199)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD55 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: LU30

Produktdetails anti-CD55 Antikörper

Verwendungszweck: Anti-CD55 [LU30], Rabbit IgG, lambda

Spezifität: The antibody binds to CD55 with a Kd of 13 nM.

Produktmerkmale: Human

Aufreinigung: Protein A affinity purified

Immunogen: Human CD55.

Isotyp: IgG lambda

Anwendungsinformationen

Applikationshinweise: The antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung: CD55

Hintergrund: DAF, Complement decay-accelerating factor

UniProt: P08174

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity