Rekombinanter CD55 Antikörper
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- Target Alle CD55 Antikörper anzeigen
- CD55 (Complement Decay-Accelerating Factor (CD55))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Chimeric
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Konjugat
- Dieser CD55 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Verwendungszweck
- Anti-CD55 [LU30], Rabbit IgG, lambda
- Spezifität
- The antibody binds to CD55 with a Kd of 13 nM.
- Produktmerkmale
- Human
- Aufreinigung
- Protein A affinity purified
- Immunogen
- Human CD55.
- Klon
- LU30
- Isotyp
- IgG lambda
- Top Product
- Discover our top product CD55 Primärantikörper
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- Applikationshinweise
- The antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks.
- Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- CD55 (Complement Decay-Accelerating Factor (CD55))
- Andere Bezeichnung
- CD55 (CD55 Produkte)
- Hintergrund
- DAF, Complement decay-accelerating factor
- UniProt
- P08174
- Pathways
- Komplementsystem, Regulation of Leukocyte Mediated Immunity
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