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Rekombinanter CD55 Antikörper

CD55 Reaktivität: Human WB, IHC, ELISA Wirt: Maus Chimeric LU30 unconjugated Recombinant Antibody

Produktnummer ABIN5668198

Datenblatt (PDF)

Target Alle CD55 Antikörper anzeigen

CD55 (Complement Decay-Accelerating Factor (CD55))

Antikörpertyp

Recombinant Antibody
Reaktivität
123

32

7

4

4

4

3

2

2

2
Human
Wirt
86

64

6

5

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
100

64

1
Chimeric
Konjugat
78

16

14

11

5

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD55 Antikörper ist unkonjugiert
Applikation
92

89

43

33

28

24

17

15

14

14

8

4

4

3

3

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Verwendungszweck

Anti-CD55 [LU30], Mouse IgG1, lambda

Spezifität

The antibody binds to CD55 with a Kd of 13 nM.

Produktmerkmale

Human

Aufreinigung

Protein A affinity purified

Immunogen

Human CD55.

Klon

LU30

Isotyp

IgG1 lambda

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anti-Complement Decay-Accelerating Factor (CD55) (AA 51-79) antibody
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anti-Complement Decay-Accelerating Factor (CD55) (AA 35-134) antibody
CD55 Reaktivität: Human WB, IF, ELISA Wirt: Maus Monoclonal 1D7 unconjugated

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anti-Complement Decay-Accelerating Factor (CD55) antibody
CD55 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (p) Wirt: Maus Monoclonal MEM-118 unconjugated

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anti-Complement Decay-Accelerating Factor (CD55) (AA 35-126) antibody
CD55 Reaktivität: Human IHC, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Complement Decay-Accelerating Factor (CD55) antibody (Biotin)
CD55 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (p) Wirt: Maus Monoclonal MEM-118 Biotin

Applikationshinweise

The antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks.

Kommentare

This chimeric mouse antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

PBS with 0.02 % Proclin 300.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Target

CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung

CD55 (CD55 Produkte)

Hintergrund

DAF, Complement decay-accelerating factor

UniProt

P08174

Pathways

Komplementsystem, Regulation of Leukocyte Mediated Immunity