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Rekombinanter ITGA4 (Natalizumab Biosimilar) Antikörper

Der Kaninchen Chimeric Anti-ITGA4 (Natalizumab Biosimilar)-Antikörper wurde für FACS und BR validiert. Er ist geeignet, ITGA4 (Natalizumab Biosimilar) in Proben von Human zu detektieren.
Produktnummer ABIN5668197

Kurzübersicht für Rekombinanter ITGA4 (Natalizumab Biosimilar) Antikörper (ABIN5668197)

Target

ITGA4 (Natalizumab Biosimilar)

Antikörpertyp

Recombinant Antibody

Reaktivität

Human

Wirt

  • 3
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 4
  • 2
Chimeric

Konjugat

  • 5
  • 1
Dieser ITGA4 (Natalizumab Biosimilar) Antikörper ist unkonjugiert

Applikation

Flow Cytometry (FACS), Blocking Reagent (BR)
  • Verwendungszweck

    Anti-Integrin alpha 4 [Natalizumab], Rabbit IgG, kappa

    Spezifität

    This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin

    Produktmerkmale

    Original Species of Ab: Human

    Original Format of Ab: IgG4

    Aufreinigung

    Protein A affinity purified

    Reinheit

    > 98 % as determined by SDS-PAGE

    Endotoxin-Niveau

    Endotoxin is < 1.0 EU/mg as determined by the LAL method

    Immunogen

    The RAMOS cell line, a non-EBV releasing cell line, injected into mice.

    Isotyp

    IgG kappa
  • Applikationshinweise

    This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.

    Kommentare

    NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target

    ITGA4 (Natalizumab Biosimilar)

    Hintergrund

    CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV

    UniProt

    P13612
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