Rekombinanter CD3 epsilon Antikörper
Kurzübersicht für Rekombinanter CD3 epsilon Antikörper (ABIN5668185)
Target
Alle CD3 epsilon (CD3E) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-CD3 epsilon [12F6], Rabbit IgG, kappa
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Spezifität
- This antibody binds to human CD3.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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Aufreinigung
- Protein A affinity purified
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Immunogen
- Human CD3
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Isotyp
- IgG kappa
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Applikationshinweise
- This antibody competes for CD3 binding with the therapeutic antibody OKT3 (Ab00122). 12F6 binding to CD3 on human T-cells stimulates the secretion of TNF-alpha, INF-gamma and IL-10. Humanized versions of this antibody are also available.
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD3 epsilon (CD3E)
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Andere Bezeichnung
- CD3 epsilon
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Hintergrund
- Leu4/T3, ET-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e
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UniProt
- P07766
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Pathways
- T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Target
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