Rekombinanter TNF alpha (Infliximab Biosimilar) Antikörper

Produktnummer ABIN5668148

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch TNF alpha (Infliximab Biosimilar) in FACS, in vivo und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter TNF alpha (Infliximab Biosimilar) Antikörper (ABIN5668148)

Target: TNF alpha (Infliximab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser TNF alpha (Infliximab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo), ELISA

Klon: CA2

Produktdetails anti-TNF alpha (Infliximab Biosimilar) Antikörper

Verwendungszweck: Anti-TNF alpha [cA2 (Infliximab)], Rabbit IgG, kappa

Spezifität: Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.

Produktmerkmale:

Original Species of Ab: Human

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Reinheit: > 98 % as determined by SDS-PAGE

Endotoxin-Niveau: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogen: Purified recombinant human TNF (rTNF).

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody can be used to detect and neutralize human TNF alpha. Unlike Adalimumab (Ab00718), Infliximab does not bind to mouse TNF alpha (Arnoult 2017, PMID: 28584008).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu TNF alpha (Infliximab Biosimilar)

Target: TNF alpha (Infliximab Biosimilar)

Substanzklasse: Biosimilar

Hintergrund: TNF-α, TNFα, TNFSF, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, TNFa

UniProt: P01375