Rekombinanter TNF alpha (Infliximab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter TNF alpha (Infliximab Biosimilar) Antikörper (ABIN7200661)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- Infliximab Biosimilar, TNF alpha Monoclonal Antibody
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Spezifität
- The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.
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Produktmerkmale
- Infliximab, a chimeric anti-TNF-α monoclonal antibody, is used to treat psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab interferes TNF-α from binding to its receptor in the cell. Mainly produced by activated macrophages (M1), Tumor necrosis factor (TNF, cachexin, cachectin, tumor necrosis factor alpha, TNFα) plays important roles in the regulation of autoimmune reaction. Syd Labs also provides the following anti-TNF antibody biosimilar protein:
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by reducing SDS-PAGE
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- The monoclonal antibody Infliximab biosimilar was produced in the Infliximab biosimilar CHO stable cell line.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- > 3 mg/mL
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Buffer
- PBS, pH 7.4, no stabilizers or preservatives.
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Konservierungsmittel
- Without preservative
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Lagerung
- 4°C,-20 °C
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Informationen zur Lagerung
- 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
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Haltbarkeit
- 12 months
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- TNF alpha (Infliximab Biosimilar)
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Andere Bezeichnung
- Infliximab Biosimilar
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Substanzklasse
- Biosimilar
Target
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