Rekombinanter TNF alpha (Infliximab Biosimilar) Antikörper

Produktnummer ABIN5668147

Dieser Anti-TNF alpha (Infliximab Biosimilar) Antikörper ist ein Human Chimeric Antikörper zur Detektion von TNF alpha (Infliximab Biosimilar) in FACS, in vivo und ELISA. Geeignet für Human.

Kurzübersicht für Rekombinanter TNF alpha (Infliximab Biosimilar) Antikörper (ABIN5668147)

Target: TNF alpha (Infliximab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Human

Klonalität: Chimeric

Konjugat: Dieser TNF alpha (Infliximab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo), ELISA

Klon: CA2

Produktdetails anti-TNF alpha (Infliximab Biosimilar) Antikörper

Verwendungszweck: Anti-TNF alpha [cA2 (Infliximab)], Human IgG1, kappa

Spezifität: Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.

Produktmerkmale:

Original Species of Ab: Human

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Reinheit: > 98 % as determined by SDS-PAGE

Endotoxin-Niveau: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogen: Purified recombinant human TNF (rTNF).

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: This antibody can be used to detect and neutralize human TNF alpha. Unlike Adalimumab (Ab00718), Infliximab does not bind to mouse TNF alpha (Arnoult 2017, PMID: 28584008).

Kommentare:

NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This is a chimeric antibody created for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu TNF alpha (Infliximab Biosimilar)

Target: TNF alpha (Infliximab Biosimilar)

Substanzklasse: Biosimilar

Hintergrund: TNF-α, TNFα, TNFSF, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, TNFa

UniProt: P01375