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BCL2A1 Antikörper

BCL2A1 Reaktivität: Human IF, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1678494
$589.88
Zzgl. Versandkosten $45.00
Lieferung in 10 bis 11 Werktagen
  • Target Alle BCL2A1 Antikörper anzeigen
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Reaktivität
    • 63
    • 24
    • 14
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 56
    • 7
    • 3
    Kaninchen
    Klonalität
    • 56
    • 10
    Polyklonal
    Konjugat
    • 30
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser BCL2A1 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 32
    • 24
    • 9
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Western Blotting (WB)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide of human BCL2A1
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide, pH 7.3.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C. Avoid freeze / thaw cycles.
  • Target
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Andere Bezeichnung
    BCL2A1 (BCL2A1 Produkte)
    Synonyme
    ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1, Bcl2a1d, BCL2A1, BCL2 related protein A1, BCL2-related protein A1, BCL2A1, Bcl2a1
    Hintergrund
    This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,BCL2A1,ACC-1,ACC-2,ACC1,ACC2,BCL2L5,BFL1,GRS,HBPA1,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,BCL2A1
    Molekulargewicht
    18 kDa/20 kDa
    Gen-ID
    597
    UniProt
    Q16548
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