BCL2A1 Antikörper

Produktnummer ABIN1678494

Dieses Anti-BCL2A1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BCL2A1 in WB und IF. Geeignet für Human.

Kurzübersicht für BCL2A1 Antikörper (ABIN1678494)

Target: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-BCL2A1 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human BCL2A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Avoid freeze / thaw cycles.

Details zu BCL2A1

Target: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Andere Bezeichnung: BCL2A1

Hintergrund: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,BCL2A1,ACC-1,ACC-2,ACC1,ACC2,BCL2L5,BFL1,GRS,HBPA1,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,BCL2A1

Molekulargewicht: 18 kDa/20 kDa

Gen-ID: 597

UniProt: Q16548