DNAI2 Antikörper (AA 1-593)

Produktnummer ABIN566265

Produktdetails anti-DNAI2 Antikörper

Target: DNAI2 (Dynein, Axonemal, Intermediate Chain 2 (DNAI2))

Bindungsspezifität: AA 1-593

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DNAI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant DNAI2.

Sequenz: MEIVYVYVKK RSEFGKQCNF SDRQAELNID IMPNPELAEQ FVERNPVDTG IQCSISMSEH EANSERFEME TRGVNHVEGG WPKDVNPLEL EQTIRFRKKV EKDENYVNAI MQLGSIMEHC IKQNNAIDIY EEYFNDEEAM EVMEEDPSAK TINVFRDPQE IKRAATHLSW HPDGNRKLAV AYSCLDFQRA PVGMSSDSYI WDLENPNKPE LALKPSSPLV TLEFNPKDSH VLLGGCYNGQ IACWDTRKGS LVAELSTIES SHRDPVYGTI WLQSKTGTEC FSASTDGQVM WWDIRKMSEP TEVVILDITK KEQLENALGA ISLEFESTLP TKFMVGTEQG IVISCNRKAK TSAEKIVCTF PGHHGPIYAL QRNPFYPKNF LTVGDWTARI WSEDSRESSI MWTKYHMAYL TDAAWSPVRP TVFFTTRMDG TLDIWDFMFE QCDPTLSLKD NGCLIACGSQ LGTTTLLEVS PGLSTLQRNE KNVASSMFER ETRREKILEA RHREMRLKEK GKAEGRDEEQ TDEELAVDLE ALVSKAEEEF FDIIFTELKK KEADAIKLTP VPQQPSPEED QVVEEGEEAA GEEGDEEVEE DLA

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: DNAI2 (AAH39582, 1 a.a. ~ 593 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 1C8

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-DNAI2 Antikörper (ABIN566265)

Ben Khelifa, Coutton, Zouari, Karaouzène, Rendu, Bidart, Yassine, Pierre, Delaroche, Hennebicq, Grunwald, Escalier, Pernet-Gallay, Jouk, Thierry-Mieg, Touré, Arnoult, Ray: "Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella." in: American journal of human genetics, Vol. 94, Issue 1, pp. 95-104, (2014) (PubMed).

Dong, Shinohara, Botilde, Nabeshima, Asai, Fukumoto, Hasegawa, Matsuo, Takeda, Shiratori, Nakamura, Hamada: "Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm." in: The Journal of cell biology, Vol. 204, Issue 2, pp. 203-13, (2014) (PubMed).

Diggle, Moore, Mali, zur Lage, Ait-Lounis, Schmidts, Shoemark, Garcia Munoz, Halachev, Gautier, Yeyati, Bonthron, Carr, Hayward, Markham, Hope, von Kriegsheim, Mitchison, Jackson, Durand, Reith et al.: "HEATR2 plays a conserved role in assembly of the ciliary motile apparatus. ..." in: PLoS genetics, Vol. 10, Issue 9, pp. e1004577, (2014) (PubMed).

Tarkar, Loges, Slagle, Francis, Dougherty, Tamayo, Shook, Cantino, Schwartz, Jahnke, Olbrich, Werner, Raidt, Pennekamp, Abouhamed, Hjeij, Köhler, Griese, Li, Lemke, Klena, Liu, Gabriel, Tobita et al.: "DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." in: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).

Loges, Olbrich, Fenske, Mussaffi, Horvath, Fliegauf, Kuhl, Baktai, Peterffy, Chodhari, Chung, Rutman, OCallaghan, Blau, Tiszlavicz, Voelkel, Witt, Zietkiewicz, Neesen, Reinhardt, Mitchison, Omran: "DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm." in: American journal of human genetics, Vol. 83, Issue 5, pp. 547-58, (2008) (PubMed).

Omran, Kobayashi, Olbrich, Tsukahara, Loges, Hagiwara, Zhang, Leblond, OToole, Hara, Mizuno, Kawano, Fliegauf, Yagi, Koshida, Miyawaki, Zentgraf, Seithe, Reinhardt, Watanabe, Kamiya, Mitchell, Takeda: "Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins." in: Nature, Vol. 456, Issue 7222, pp. 611-6, (2008) (PubMed).

Details zu DNAI2

Target: DNAI2 (Dynein, Axonemal, Intermediate Chain 2 (DNAI2))

Andere Bezeichnung: DNAI2 (DNAI2 Produkte)

Hintergrund: Full Gene Name: dynein, axonemal, intermediate chain 2
Synonyms: CILD9

Gen-ID: 64446