ABHD5 Antikörper (AA 1-349)

Produktnummer ABIN565526

Der Maus Monoklonal Anti-ABHD5-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, ABHD5 in Proben von Human zu detektieren. Es sind 11+ Publikationen verfügbar.

Kurzübersicht für ABHD5 Antikörper (AA 1-349) (ABIN565526)

Target: ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ABHD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1F3

Produktdetails anti-ABHD5 Antikörper

Bindungsspezifität: AA 1-349

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant ABHD5.

Sequenz: MAAEEEEVDS ADTGERSGWL TGWLPTWCPT SISHLKEAEE KMLKCVPCTY KKEPVRISNG NKIWTLKFSH NISNKTPLVL LHGFGGGLGL WALNFGDLCT NRPVYAFDLL GFGRSSRPRF DSDAEEVENQ FVESIEEWRC ALGLDKMILL GHNLGGFLAA AYSLKYPSRV NHLILVEPWG FPERPDLADQ DRPIPVWIRA LGAALTPFNP LAGLRIAGPF GLSLVQRLRP DFKRKYSSMF EDDTVTEYIY HCNVQTPSGE TAFKNMTIPY GWAKRPMLQR IGKMHPDIPV SVIFGARSCI DGNSGTSIQS LRPHSYVKTI AILGAGHYVY ADQPEEFNQK VKEICDTVD

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: ABHD5 (AAH21958, 1 a.a. ~ 349 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ABHD5 Antikörper (ABIN565526)

Hofer, Boeszoermenyi, Jaeger, Feiler, Arthanari, Mayer, Zehender, Rechberger, Oberer, Zimmermann, Lass, Haemmerle, Breinbauer, Zechner, Preiss-Landl: "Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling." in: The Journal of biological chemistry, Vol. 290, Issue 30, pp. 18438-53, (2015) (PubMed).

Kurtz, Peck, Fannin, Beysen, Miao, Landstreet, Ding, Turaga, Lund, Turner, Biddinger, Vickers, Sethupathy: "MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes." in: Diabetes, Vol. 63, Issue 9, pp. 3141-8, (2014) (PubMed).

Patel, Yang, Kozusko, Saudek, Savage: "Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 involved in sequestering ABHD5 and suppressing basal lipolysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 25, pp. 9163-8, (2014) (PubMed).

Camus, Schweiger, Herker, Harris, Kondratowicz, Tsou, Farese, Herath, Previs, Roddy, Pinto, Zechner, Ott et al.: "The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid ..." in: The Journal of biological chemistry, Vol. 289, Issue 52, pp. 35770-80, (2014) (PubMed).

Pollak, Schweiger, Jaeger, Kolb, Kumari, Schreiber, Kolleritsch, Markolin, Grabner, Heier, Zierler, Rülicke, Zimmermann, Lass, Zechner, Haemmerle: "Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier." in: Journal of lipid research, Vol. 54, Issue 4, pp. 1092-102, (2013) (PubMed).

Guo, Ma, Kadegowda, Betters, Xie, Liu, Liu, Miao, Ou, Su, Zheng, Xue, Shi, Yu: "Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice." in: Journal of lipid research, Vol. 54, Issue 8, pp. 2109-20, (2013) (PubMed).

Louche, Badin, Montastier, Laurens, Bourlier, de Glisezinski, Thalamas, Viguerie, Langin, Moro: "Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 12, pp. 4863-71, (2013) (PubMed).

Inoue, Kobayashi, Inoguchi, Sonoda, Maeda, Hirata, Fujimura, Miura, Hirano, Takayanagi: "Downregulation of adipose triglyceride lipase in the heart aggravates diabetic cardiomyopathy in db/db mice." in: Biochemical and biophysical research communications, Vol. 438, Issue 1, pp. 224-9, (2013) (PubMed).

Grall, Guaguère, Planchais, Grond, Bourrat, Hausser, Hitte, Le Gallo, Derbois, Kim, Lagoutte, Degorce-Rubiales, Radner, Thomas, Küry, Bensignor, Fontaine, Pin, Zimmermann, Zechner, Lathrop, Galibert et al.: "PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. ..." in: Nature genetics, Vol. 44, Issue 2, pp. 140-7, (2012) (PubMed).

Stenson, Rydén, Venteclef, Dahlman, Pettersson, Mairal, Aström, Blomqvist, Wang, Jocken, Clément, Langin, Arner, Laurencikiene: "Liver X receptor (LXR) regulates human adipocyte lipolysis." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 370-9, (2011) (PubMed).

Kinney, Qiao, Levaugh, Shao: "B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice." in: Endocrinology, Vol. 151, Issue 8, pp. 3624-32, (2010) (PubMed).

Details zu ABHD5

Target: ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))

Andere Bezeichnung: ABHD5

Hintergrund: Full Gene Name: abhydrolase domain containing 5
Synonyms: CDS,CGI58,IECN2,MGC8731,NCIE2

Gen-ID: 51099

Pathways: Lipid Metabolism