RNF139 Antikörper (AA 565-664)
Kurzübersicht für RNF139 Antikörper (AA 565-664) (ABIN564886)
Target
Alle RNF139 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 565-664
-
Verwendungszweck
- Mouse polyclonal antibody raised against a partial recombinant RNF139.
-
Sequenz
- HYFHALCLRK WLYIQDTCPM CHQKVYIEDD IKDNSNVSNN NGFIPPNETP EEAVREAAAE SDRELNEDDS TDCDDDVQRE RNGVIQHTGA AAEEFNDDTD
-
Kreuzreaktivität
- Human
-
Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
-
Immunogen
- RNF139 (NP_009149, 565 a.a. ~ 664 a.a) partial recombinant protein with GST tag.
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- 50 % glycerol
-
Handhabung
- Aliquot to avoid repeated freezing and thawing.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
-
-
The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways." in: Molecular cancer research : MCR, Vol. 8, Issue 1, pp. 93-106, (2010) (PubMed).
: "The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces ..." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28995-9004, (2009) (PubMed).
: "The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER." in: The Journal of cell biology, Vol. 186, Issue 5, pp. 685-92, (2009) (PubMed).
: "RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene." in: Oncogene, Vol. 26, Issue 16, pp. 2263-71, (2007) (PubMed).
: "
-
The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways." in: Molecular cancer research : MCR, Vol. 8, Issue 1, pp. 93-106, (2010) (PubMed).
-
- RNF139 (Ring Finger Protein 139 (RNF139))
-
Andere Bezeichnung
- RNF139
-
Hintergrund
-
Full Gene Name: ring finger protein 139
Synonyms: HRCA1,MGC31961,RCA1,TRC8 -
Gen-ID
- 11236
-
NCBI Accession
- NM_007218
Target
-