POLI Antikörper (AA 616-715)
Kurzübersicht für POLI Antikörper (AA 616-715) (ABIN564869)
Target
Alle POLI Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 616-715
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Verwendungszweck
- Mouse monoclonal antibody raised against a partial recombinant POLI.
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Sequenz
- PQGFHFTNSN PAVSAFHSFP NLQSEQLFSR NHTTDSHKQT VATDSHEGLT ENREPDSVDE KITFPSDIDP QVFYELPEAV QKELLAEWKR AGSDFHIGHK
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Kreuzreaktivität
- Human
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Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- POLI (AAH32662, 616 a.a. ~ 715 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotyp
- IgG3
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1x PBS, pH 7.4
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication." in: Molecular and cellular biology, Vol. 35, Issue 4, pp. 699-715, (2015) (PubMed).
: "Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation." in: Journal of nucleic acids, Vol. 2010, pp. 750296, (2010) (PubMed).
: "Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations." in: Cancer research, Vol. 67, Issue 7, pp. 3018-26, (2007) (PubMed).
: "
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Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication." in: Molecular and cellular biology, Vol. 35, Issue 4, pp. 699-715, (2015) (PubMed).
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- POLI (Polymerase (DNA Directed) iota (POLI))
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Andere Bezeichnung
- POLI
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Hintergrund
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Full Gene Name: polymerase (DNA directed) iota
Synonyms: RAD30B,RAD3OB -
Gen-ID
- 11201
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Pathways
- DNA Reparatur
Target
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