GLA Antikörper (AA 218-275)
Kurzübersicht für GLA Antikörper (AA 218-275) (ABIN5647751)
Target
Alle GLA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 218-275
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Aufreinigung
- Antigen affinity purified
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Immunogen
- Amino acids 218-275 (DIQYYCNHWRNFDDVYDSWESIKNILSWTVVYQKEIVEVA-mouse) were used as the immunogen for the Gla antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the Gla antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- -20 °C
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Informationen zur Lagerung
- After reconstitution, the Gla antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- GLA (Galactosidase, alpha (GLA))
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Andere Bezeichnung
- Gla / Galactosidase alpha
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Hintergrund
- Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
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UniProt
- P51569
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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