ASIC3 Antikörper (AA 55-83)

Produktnummer ABIN5647476

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ASIC3 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ASIC3 Antikörper (AA 55-83) (ABIN5647476)

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASIC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ASIC3 Antikörper

Bindungsspezifität: AA 55-83

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 55-83 from the human protein was used as the immunogen for this ASIC3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ASIC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ASIC3

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Andere Bezeichnung: ACCN3 / ASIC3

Hintergrund: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1/ASIC2 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms.

UniProt: Q9UHC3