Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ACO2 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.
Western blot: 1:500-1000,IHC (Paraffin): 1:10-1:50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Aconitase 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
ACO2
(Aconitase 2, Mitochondrial (ACO2))
Andere Bezeichnung
Aconitase 2
Hintergrund
ACO2/Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.