Thymic Stromal Lymphopoietin Antikörper

Produktnummer ABIN5647286

Der Kaninchen Polyklonal anti-Thymic Stromal Lymphopoietin Antikörper (ABIN5647286) detektiert spezifisch Thymic Stromal Lymphopoietin in WB und ELISA (Capture). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Thymic Stromal Lymphopoietin Antikörper (ABIN5647286)

Target: Thymic Stromal Lymphopoietin (TSLP)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thymic Stromal Lymphopoietin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA (Capture)

Produktdetails anti-Thymic Stromal Lymphopoietin Antikörper

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids KVTTNKCLEQVSQLQGLWRRFNRPLLKQQ were used as the immunogen for the TSLP antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TSLP antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the TSLP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Thymic Stromal Lymphopoietin

Target: Thymic Stromal Lymphopoietin (TSLP)

Andere Bezeichnung: TSLP

Hintergrund: Thymic stromal lymphopoietin, also called TSLP is a protein belonging to the cytokine family. This gene is mapped to 5q22.1. It encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2(TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.

UniProt: Q969D9