Thymic Stromal Lymphopoietin Antikörper

Produktnummer ABIN5647286

Dieses Anti-Thymic Stromal Lymphopoietin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Thymic Stromal Lymphopoietin in WB und ELISA (Capture). Geeignet für Human und Maus.

Kurzübersicht für Thymic Stromal Lymphopoietin Antikörper (ABIN5647286)

Target: Thymic Stromal Lymphopoietin (TSLP)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thymic Stromal Lymphopoietin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA (Capture)

Produktdetails anti-Thymic Stromal Lymphopoietin Antikörper

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids KVTTNKCLEQVSQLQGLWRRFNRPLLKQQ were used as the immunogen for the TSLP antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TSLP antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the TSLP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Thymic Stromal Lymphopoietin

Target: Thymic Stromal Lymphopoietin (TSLP)

Andere Bezeichnung: TSLP

Hintergrund: Thymic stromal lymphopoietin, also called TSLP is a protein belonging to the cytokine family. This gene is mapped to 5q22.1. It encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2(TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.

UniProt: Q969D9