SH2D1A Antikörper (AA 1-128)

Produktnummer ABIN561703

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SH2D1A in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für SH2D1A Antikörper (AA 1-128) (ABIN561703)

Target: SH2D1A (SH2 Domain Containing 1A (SH2D1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SH2D1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 1C9

Produktdetails anti-SH2D1A Antikörper

Bindungsspezifität: AA 1-128

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant SH2D1A.

Sequenz: MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: SH2D1A (AAH20732, 1 a.a. ~ 128 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-SH2D1A Antikörper (ABIN561703)

Menard, Cantaert, Chamberlain, Tangye, Riminton, Church, Klion, Cunningham-Rundles, Nichols, Meffre: "Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance." in: The Journal of allergy and clinical immunology, Vol. 133, Issue 4, pp. 1149-61, (2014) (PubMed).

Meazza, Tuberosa, Cetica, Falco, Parolini, Grieve, Griffiths, Sieni, Marcenaro, Micalizzi, Montin, Fagioli, Moretta, Mingari, Moretta, Notarangelo, Bottino, Aricò, Pende: "Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis." in: The Journal of allergy and clinical immunology, Vol. 134, Issue 6, pp. 1381-1387.e7, (2014) (PubMed).

Palendira, Low, Bell, Ma, Abbott, Phan, Riminton, Choo, Smart, Lougaris, Giliani, Buckley, Grimbacher, Alvaro, Klion, Nichols, Adelstein, Rickinson, Tangye: "Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus." in: The Journal of experimental medicine, Vol. 209, Issue 5, pp. 913-24, (2012) (PubMed).

Palendira, Low, Chan, Hislop, Ho, Phan, Deenick, Cook, Riminton, Choo, Loh, Alvaro, Booth, Gaspar, Moretta, Khanna, Rickinson, Tangye: "Molecular pathogenesis of EBV susceptibility in XLP as revealed by analysis of female carriers with heterozygous expression of SAP." in: PLoS biology, Vol. 9, Issue 11, pp. e1001187, (2011) (PubMed).

Ma, Suryani, Avery, Chan, Nanan, Santner-Nanan, Deenick, Tangye: "Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12." in: Immunology and cell biology, Vol. 87, Issue 8, pp. 590-600, (2009) (PubMed).

Details zu SH2D1A

Target: SH2D1A (SH2 Domain Containing 1A (SH2D1A))

Andere Bezeichnung: SH2D1A

Hintergrund: Full Gene Name: SH2 domain protein 1A
Synonyms: DSHP,EBVS,FLJ18687,FLJ92177,IMD5,LYP,MTCP1,SAP,XLP,XLPD

Gen-ID: 4068

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process