HSD17B3 Antikörper (AA 29-119)

Produktnummer ABIN561372

Zitiert in 3+ Publikationen. Der Maus Polyklonal anti-HSD17B3 Antikörper (ABIN561372) detektiert spezifisch HSD17B3 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HSD17B3 Antikörper (AA 29-119) (ABIN561372)

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser HSD17B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HSD17B3 Antikörper

Bindungsspezifität: AA 29-119

Verwendungszweck: Mouse polyclonal antibody raised against a partial recombinant HSD17B3.

Sequenz: RCVLLNYWKV LPKSFLRSMG QWAVITGAGD GIGKAYSFEL AKRGLNVVLI SRTLEKLEAI ATEIERTTGR SVKIIQADFT KDDIYEHIKE K

Kreuzreaktivität: Human, Maus

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: HSD17B3 (NP_000188, 29 a.a. ~ 119 a.a) partial recombinant protein with GST tag.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 % glycerol

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-HSD17B3 Antikörper (ABIN561372)

Fokidis, Yieng Chin, Ho, Adomat, Soma, Fazli, Nip, Cox, Krystal, Zoubeidi, Tomlinson Guns: "A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice." in: The Journal of steroid biochemistry and molecular biology, Vol. 150, pp. 35-45, (2015) (PubMed).

Ming, Pham, Deb, Chin, Kharmate, Adomat, Beheshti, Locke, Guns: "Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo." in: The Journal of steroid biochemistry and molecular biology, Vol. 143, pp. 19-28, (2014) (PubMed).

Locke, Guns, Lubik, Adomat, Hendy, Wood, Ettinger, Gleave, Nelson: "Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer." in: Cancer research, Vol. 68, Issue 15, pp. 6407-15, (2008) (PubMed).

Details zu HSD17B3

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Andere Bezeichnung: HSD17B3

Hintergrund: Full Gene Name: hydroxysteroid (17-beta) dehydrogenase 3
Synonyms: EDH17B3,SDR12C2

Gen-ID: 3293

NCBI Accession: NM_000197

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis