HSD17B1 Antikörper (AA 189-285)

Produktnummer ABIN561371

Der Maus Monoklonal Anti-HSD17B1-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, HSD17B1 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für HSD17B1 Antikörper (AA 189-285) (ABIN561371)

Target: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSD17B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2E5

Produktdetails anti-HSD17B1 Antikörper

Bindungsspezifität: AA 189-285

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant HSD17B1.

Sequenz: VHTAFMEKVL GSPEEVLDRT DIHTFHRFYQ YLAHSKQVFR EAAQNPEEVA EVFLTALRAP KPTLRYFTTE RFLPLLRMRL DDPSGSNYVT AMHREVF

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: HSD17B1 (NP_000404, 189 a.a. ~ 285 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-HSD17B1 Antikörper (ABIN561371)

McNamara, Oguro, Omata, Kikuchi, Guestini, Suzuki, Yang, Abe, Hirakawa, Brown, Takanori, Ohuchi, Sasano: "The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer." in: Breast cancer research and treatment, Vol. 161, Issue 2, pp. 213-227, (2016) (PubMed).

Inoue, Miki, Abe, Hatori, Hosaka, Kariya, Kakuo, Fujimura, Hachiya, Aiba, Sasano: "The role of estrogen-metabolizing enzymes and estrogen receptors in human epidermis." in: Molecular and cellular endocrinology, Vol. 344, Issue 1-2, pp. 35-40, (2011) (PubMed).

Chanplakorn, Chanplakorn, Suzuki, Ono, Chan, Miki, Saji, Ueno, Toi, Sasano: "Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients." in: Breast cancer research and treatment, Vol. 120, Issue 3, pp. 639-48, (2010) (PubMed).

Details zu HSD17B1

Target: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Andere Bezeichnung: HSD17B1

Hintergrund: Full Gene Name: hydroxysteroid (17-beta) dehydrogenase 1
Synonyms: EDH17B2,EDHB17,HSD17,MGC138140,SDR28C1

Gen-ID: 3292

NCBI Accession: NM_000413

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis